Deep inspiration and airway physiology: human, canine, porcine, or bovine?
نویسندگان
چکیده
Peter B. Noble, Jeremy M. Hernandez, Howard W. Mitchell, and Luke J. Janssen Division of Clinical Sciences, Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, Perth; Physiology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Perth, Australia; and Firestone Institute for Respiratory Health, Father Sean O’Sullivan Research Centre, and Department of Medicine, McMaster University, St. Joseph’s Hospital, Hamilton, Ontario, Canada
منابع مشابه
Receptors and signaling pathway underlying relaxations to isoprostanes in canine and porcine airway smooth muscle.
Using muscle bath techniques, we examined the inhibitory activities of several E- and F-ring isoprostanes in canine and porcine airway smooth muscle. 8-Isoprostaglandin E1 and 8-isoprostaglandin E2 (8-iso PGE2) reversed cholinergic tone in a concentration-dependent manner, whereas the F-ring isoprostanes were ineffective. Desensitization with 8-iso-PGE2 and PGE2 implicated isoprostane activity ...
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عنوان ژورنال:
- Journal of applied physiology
دوره 109 3 شماره
صفحات -
تاریخ انتشار 2010